On Friday evening at 10:47pm, officers were called to reports of a collision.
A car collided with a pedestrian at the junction of Spring Vale and Oldham Road - opposite the Hare and Hounds Pub in Middleton.
The driver did not remain at the scene.
One man was taken to hospital for treatment of serious injuries, although these are not believed to be life-threatening.
An investigation is underway and officers are now appealing for witnesses or anyone who may have footage of the incident - including CCTV or dashcam - to please get in touch.
You can do so by calling GMP's Serious Collision Investigation Unit on 0161 856 4741 quoting incident 3763 of 10/03/2023.
A report can also be made via GMP's website: www.gmp.police.uk
Alternatively, call the independent charity, Crimestoppers, anonymously on 0800 555 111.
